Question

) Which of the following is a benefit of the oral route of administration?

Ease of administration
Direct delivery to the systemic circulation
Beneficial for the delivery of peptides
Rapid onset of action
2) A pharmacist would like to select the smallest size capsule to make a compounded preparation. Which of the following sizes should the pharmacist select?

000
0
2
5
3) Which of the following is true regarding the process of hand-filling capsules?

The capsule should be aggressively pressed into the powder mixture while filling the capsules
Once the capsule has been filled, the amount of powder inside can no longer be adjusted
Compounding personnel will feel a slight resistance as the capsule is pressed into the powder, which indicates it is full
Gloves should never be worn during the process of hand-filling capsules
4) Which of the following is true regarding the selection of excipients for use in a tablet preparation?

Binders aid in the breakdown of tablets and include PEG and starch
Lubricants help to mask the bitter tastes of APIs and include water
Binders hold powders together and include water and alcohol
Disintegrants prevent sticking and include calcium stearate
5) A pharmacy technician is preparing a powder mixture for use in a capsule. The technician reduces the particle size by grinding the solids into a fine powder and simultaneously mixing them. Which of the following techniques are they using?

The Rule of Sixes
Trituration
Levigation
Pulverization by intervention
6) Which of the following is true regarding the preparation of a solution?

pH is a minor consideration as this has minimal effects on drug stability and activity
Polar solvents should be used to dissolve nonpolar solutes
The most common solvent used in solutions is ethanol
The most common technique for preparing a solution is dissolving a drug into a solvent by stirring
7) A pharmacist is sharing tips for preparing solutions with a pharmacy intern. Which of the following is a correct tip for solution preparation?

Preparations should be stirred vigorously to ensure foaming occurs
Stirring rods should be used when adding sufficient volume of a solvent
Salts should be dissolved in small quantities of water before adding viscous vehicles
Two liquids should be combined with minimal stirring to decrease the chance of instability occurring
8) Which of the following is the first step when preparing a suspension?

Wetting the active pharmaceutical ingredient
Achieving particle size reduction of the active pharmaceutical ingredient
Blending the active pharmaceutical ingredient with the vehicle
Mixing the active pharmaceutical ingredient and wetting agent to form a thick paste
9) Which of the following is true regarding the preparation of lozenges?

Flavoring agents are typically added at concentrations greater than those used in regular candies
Preparing soft lozenges involves the use of firm candy bases derived from sugar and syrup
Lozenges should only be prepared using a mold
Chewable lozenges can be prepared by heating the ingredients to a high temperature, pouring them into molds, and then cutting them into ribbons after cooling
10) A pharmacy technician is completing quality control procedures for a recently prepared batch of capsules. Which of the following is an appropriate quality control check for this preparation?

Dispersibility
Pourability
Uniformity
Extent of settling

Answer 1

1) Ease of administration

2) 5

3) Compounding personnel will feel a slight resistance as the capsule is pressed into the powder, which indicates it is full

4) Binders hold powders together and include water and alcohol

5) Trituration

6) The most common technique for preparing a solution is dissolving a drug into a solvent by stirring

7) Salts should be dissolved in small quantities of water before adding viscous vehicles

8) Achieving particle size reduction of the active pharmaceutical ingredient

9) Flavoring agents are typically added at concentrations greater than those used in regular candies

10) Uniformity