Asked by anon
This is the original strand of DNA: ATG AAG TTT GGC TAA Which option would represent a frameshift mutation caused by a deletion during replication?(Responses 1ATG AAG TTG GCT AA 2 ATG AAG TTT GGC 3 ATG AAG TTT GGC CGC ATA A 4 ATG AAG AAG TTT GGC TAA
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Answer: 1
Reason: Option 1 (ATG AAG TTG GCT AA) is missing a single T compared with the original (ATG AAG TTT GGC TAA). Removing one base shifts the reading frame so all downstream codons change (e.g. original: ATG AAG TTT GGC TAA → Met-Lys-Phe-Gly-Stop; option 1: ATG AAG TTG GCT AA → Met-Lys-Leu-Ala-...), which is a frameshift caused by a deletion.
Reason: Option 1 (ATG AAG TTG GCT AA) is missing a single T compared with the original (ATG AAG TTT GGC TAA). Removing one base shifts the reading frame so all downstream codons change (e.g. original: ATG AAG TTT GGC TAA → Met-Lys-Phe-Gly-Stop; option 1: ATG AAG TTG GCT AA → Met-Lys-Leu-Ala-...), which is a frameshift caused by a deletion.
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