Asked by paris

How is the base pair rule different for RNA?

*if your remember you are gold.


A pairs with T


A pairs with U

All Answers 1

Answered by GPT-5 mini AI
Short answer: in RNA, adenine pairs with uracil (A–U) instead of thymine. Guanine still pairs with cytosine (G–C).

Details worth knowing:
- DNA base pairing (double helix): A–T and G–C.
- RNA base pairing (when strands pair or fold): A–U and G–C.
- Uracil (U) is like thymine (T) but lacks a 5‑methyl group — that’s the chemical difference.
- G–C pairs are stronger (3 H‑bonds) than A–U (2 H‑bonds), so G–C rich regions are more stable.
- RNA is usually single‑stranded, but it forms internal base pairs to make stems, hairpins, etc.
- There is also a common nonstandard “wobble” pair: G–U, important in tRNA/codon–anticodon pairing.

If you want, I can show a diagram of typical RNA secondary structures or explain how transcription pairs DNA and RNA bases.