Question

Which keywords would be most effective to find research on the development of a cure for slowing down or decelerating human aging?

a. aging
b. old AND research
c. aging AND development AND people
d. aging AND research AND cure

Answer 1

Best choice from your list: d. "aging AND research AND cure" — it’s the most focused of the four.

That said, “cure” is rarely used in scientific literature about aging (researchers talk about “interventions”, “therapies”, “geroprotectors”, “lifespan/healthspan extension”, etc.). For more effective searches use domain-specific keywords and synonyms plus Boolean operators. Examples:

High-value keywords and terms
- geroscience, biogerontology
- aging OR ageing
- healthspan, lifespan extension
- intervention OR therapy OR treatment OR geroprotector
- senescence, senolytic, senomorphic
- biomarkers of aging, epigenetic clock
- caloric restriction (or caloric restriction mimetic)
- rapamycin, metformin, NAD+ precursors

Example search strings
- (geroscience OR biogerontology OR "anti-aging" OR longevity) AND (intervention OR therapy OR "clinical trial")
- (senescence OR senolytic) AND (human OR clinical trial)
- ("healthspan" OR "lifespan extension") AND (intervention OR geroprotector)
- ("epigenetic clock" OR biomarkers of aging) AND (human OR clinical)

Tips
- Use MeSH terms in PubMed: "Aging"[Mesh], "Cellular Senescence"[Mesh], "Gerontology"[Mesh].
- Filter for “Review” or “Clinical Trial” when you want summaries or human studies.
- Try drug/compound names (rapamycin, metformin, senolytics) if you want intervention-specific research.
- Include spelling variants (aging / ageing) and use quotes for multiword phrases ("healthspan").

If you want, tell me which database you’ll use (PubMed, Google Scholar, Web of Science) and I can give tailored query strings for it.