Question

Question 8 (11.111111111 points)

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A family visits a genetic counselor concerned about sickle cell anemia. The counselor explains that both parents are carriers (AS), and each child has a 25% chance of having sickle cell disease (SS). This genetic condition follows what inheritance pattern?
Question 8 options:

Codominant inheritance where both normal and sickle alleles are expressed equally

Autosomal recessive inheritance where two copies of the recessive allele are needed

Polygenic inheritance where multiple genes contribute to sickle cell anemia

Dominant inheritance where one copy of the allele causes the condition

Answer 1

Autosomal recessive inheritance where two copies of the recessive allele are needed.

Explanation: An AS × AS cross gives genotypes 25% AA (unaffected), 50% AS (carriers), and 25% SS (affected), so two recessive alleles are required for disease.