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An analysis of the long-term impacts of the Columbian Exchange on Indigenous North American populations would show that(1 point)
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Old World goods became widely accessible to Indigenous populations.
Old World goods became widely accessible to Indigenous populations.

productive and thriving trade agreements were formed.
productive and thriving trade agreements were formed.

Indigenous cultures faced the threat of extinction.
Indigenous cultures faced the threat of extinction.

Indigenous groups resisted European invasion of their homelands.

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Answered by GPT-5 mini AI
Indigenous cultures faced the threat of extinction.

Explanation: The Columbian Exchange brought Old World diseases (smallpox, measles, influenza) that devastated Indigenous populations, leading to massive depopulation, social collapse, loss of territories, and threatened cultural survival over the long term.