Question

) Which of the following statements regarding obesity is false?

Obesity may be associated with type 2 diabetes, high blood pressure, sleep apnea, and high cholesterol.
Obesity may lead to an increased risk of early death.
Obesity makes medical issues easier to treat as patients are seen by providers more often.
Obesity can be associated with a stigma that may affect a person’s quality of life.
2) Which of the following atypical antipsychotics has been most frequently associated with weight gain?

Aripiprazole
Olanzapine
Risperidone
Lurasidone
3) Psychiatric patients may have factors that contribute to weight gain including:

A more active lifestyle than those without psychiatric disorders.
Psychiatric patients are physically unable to stop eating when they are full.
All antipsychotics cause significant weight gain.
Paranoia or hospitalization may cause an individual to be more sedentary than desired.
4) Which medication used to manage diabetes has been used to help patients with antipsychotic-induced weight gain?

Glyburide
Metformin
Pioglitazone
Insulin
5) Which of the following statements is true regarding antidepressants and weight gain?

Tricyclic antidepressants do not typically cause weight gain.
Weight gain is not a barrier to compliance with antidepressant medications.
Bupropion is associated with the largest amount of weight gain of all antidepressants.
Patients who use SSRIs for less than six months are less likely to have weight gain.
6) Which of the following is correct about weight gain and corticosteroid therapy?

High cortisol levels can lead to decreased appetite.
Chronic corticosteroid therapy activates the endocannabinoid system and INCREASES energy expenditure.
Inhaled corticosteroids are the corticosteroid form that is most likely to increase body weight significantly.
Long-term glucocorticoid therapy has long been associated with weight gain.
7) The Endocrine Society currently recommends:

Weight-losing and weight-neutral medications as first- and second-line agents for the management of type 2 diabetes in patients who are overweight.
All patients with diabetes should be on high-dose insulin regimens.
All patients with type 2 diabetes who have hypertension and are obese should be on beta blockers.
Long-term corticosteroids should be used first-line in all patients with chronic inflammatory disease.
8) Which of the following situations could a pharmacy technician refer to the pharmacist regarding medication that might be associated with increased weight gain?

An over-the-counter orlistat container purchased with prescription nonsteroidal anti-inflammatory topical cream
An over-the-counter orlistat container purchased with a high-dose prescription amitriptyline refill request
An over-the-counter bisacodyl laxative container purchased with a prescription angiotensin receptor blocker
An over-the-counter bisacodyl laxative container purchased with a beta blocker glaucoma eye drop prescription
9) Lifestyle changes can help patients to prevent medication-related weight gain. Which of the following suggestions may be helpful when counseling patients?

Eating a diet high in carbohydrates and processed food is an efficient way to avoid weight gain.
Physical movement and working out are the only factors that can help to prevent weight gain or reduce weight.
Small daily activities should be considered, like parking the car further from the destination to walk more or taking the stairs instead of the elevator.
Once medications are discontinued, all gained weight is lost within two months.
10) Pharmacy teams can help patients prevent medication-related weight gain in the following ways except:

Working individually or as a collaborative practice team to provide education and consults.
Screening for patients who are at increased risk of weight gain at the start of therapy may lead to weight gain.
Providing support and motivation to patients who are struggling with medication-related weight gain.
Recommending a patient stop a medication immediately if they notice weight gain.

Answer 1

1) "Obesity makes medical issues easier to treat as patients are seen by providers more often." (this is false)

2) Olanzapine

3) "Paranoia or hospitalization may cause an individual to be more sedentary than desired."

4) Metformin

5) "Patients who use SSRIs for less than six months are less likely to have weight gain." (true)

6) "Long-term glucocorticoid therapy has long been associated with weight gain."

7) "Weight-losing and weight-neutral medications as first- and second-line agents for the management of type 2 diabetes in patients who are overweight."

8) An over-the-counter orlistat purchased with a high‑dose prescription amitriptyline refill request

9) "Small daily activities should be considered, like parking the car further from the destination to walk more or taking the stairs instead of the elevator."

10) "Recommending a patient stop a medication immediately if they notice weight gain."