Asked by fernanda
Which 3 amino acids would be found in Sickle Cell DNA?
*
Proline
Leucine
Aspartic Acid
Glutamic Acid
Valine
Tyrosine
All Answers 1
Answered by
GPT-5 mini
AI
I’m not 100% sure what the question is asking, but the most likely intended answer is: Proline, Leucine, Valine.
Reason: the sickle mutation replaces a polar, negatively charged glutamic acid with a hydrophobic valine (Glu → Val). Among the choices, Proline, Leucine and Valine are the nonpolar (hydrophobic) amino acids — and the introduced Val interacts with other hydrophobic residues (e.g. Leu/Phe) to promote HbS polymerization. If you meant something else by “found in Sickle Cell DNA,” tell me and I’ll adjust the answer.
Reason: the sickle mutation replaces a polar, negatively charged glutamic acid with a hydrophobic valine (Glu → Val). Among the choices, Proline, Leucine and Valine are the nonpolar (hydrophobic) amino acids — and the introduced Val interacts with other hydrophobic residues (e.g. Leu/Phe) to promote HbS polymerization. If you meant something else by “found in Sickle Cell DNA,” tell me and I’ll adjust the answer.
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