Question

Primary lateral sclerosis is a disease that affects the body's ability to react to stimuli and causes a person to have difficulty moving the legs, body trunk, arms, hands, and face.

Which specialized cells are most affected by this disease?

epithelial cells, hepatocytes
neurons, epithelial cells
muscle cells, neurons
hepatocytes, muscle cells

Answer 1

muscle cells, neurons

Primary lateral sclerosis is a motor neuron disease that primarily damages neurons (upper motor neurons). Loss of neural input leads to impaired muscle function and secondary muscle atrophy, so both neurons and muscle cells are the relevant specialized cell types.