Question

Which best compares self-renewal and differentiation?

Both are processes that are the result of stem cell division.
Both create more of the same types of cells.
Both form specialized cells.
Both depend on gene expression.

Answer 1

Both depend on gene expression.

Explanation: self-renewal and differentiation are controlled by different gene-expression programs — self-renewal maintains expression of stemness genes, while differentiation activates lineage-specific genes and represses stemness genes.