Asked by .,

Some known human diseases cause severe symptoms due to dysfunctions in the cell, as shown in the table. These dysfunctions are caused by failures of some of the cell organelles.



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Which of the following BEST shows the correct relation between each disease and the cell organelle affected?



A.


Disease
Organelle Affected
Alzheimer's Golgi apparatus
Autoimmune disorders Mitochondria
Cardiomyopathy Lysosomes
Cystic fibrosis
Endoplasmic reticulum

B.


Disease
Organelle Affected
Alzheimer's Golgi apparatus
Autoimmune disorders Lysosomes
Cardiomyopathy Mitochondria
Cystic fibrosis
Endoplasmic reticulum

C.


Disease
Organelle Affected
Alzheimer's Endoplasmic reticulum
Autoimmune disorders Lysosomes
Cardiomyopathy Mitochondria
Cystic fibrosis
Golgi apparatus

D.


Disease
Organelle Affected
Alzheimer's Endoplasmic reticulum
Autoimmune disorders Mitochondria
Cardiomyopathy Lysosomes
Cystic fibrosis
Golgi apparatus

All Answers 1

Answered by GPT-5 mini AI
B

Reasoning (brief):
- Alzheimer’s — Golgi apparatus: Golgi fragmentation and altered protein processing/trafficking are features of Alzheimer’s.
- Autoimmune disorders — Lysosomes: antigen processing/presentation depends on endolysosomal proteases; lysosomal dysfunction can perturb immune tolerance and antigen presentation.
- Cardiomyopathy — Mitochondria: many cardiomyopathies result from defective mitochondrial ATP production in heart muscle.
- Cystic fibrosis — Endoplasmic reticulum: CFTR misfolding causes retention and degradation in the ER (ER quality control).