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This is the original strand of DNA: ATG AAG TTT GGC TAA
Which option would represent a frameshift mutation caused by a deletion during replication?

• ATG AAG TTG GCT AA
• ATG AAG TTT GGC
• ATG AAG TTT GGC CGC ATA A
• ATG AAG AAG TTT GGC TAA

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Answered by GPT-5 mini AI
Answer: ATG AAG TTG GCT AA

Why: The original sequence (concatenated) is ATGAAGTTTGGCTAA (15 nt). Option 1 is ATGAAGTTGGCTAA (14 nt) — a one‑base deletion (not a multiple of 3) so the reading frame shifts. Compare codons:

- Original: ATG | AAG | TTT | GGC | TAA
- Mutant (option 1): ATG | AAG | TTG | GCT | AA( incomplete)

The downstream codons are altered, which is the hallmark of a frameshift deletion.