When Sal goes to the bathroom, he notices that his urine is very dark. He knows this means he is dehydrated, s

Question

When Sal goes to the bathroom, he notices that his urine is very dark. He knows this means he is dehydrated, so he makes sure to drink extra water. Which hormone is MOST responsible for causing Sal's urine to darken, warning him his homeostasis is off?

GPT-5 mini · Answer

Antidiuretic hormone (ADH, aka vasopressin) from the posterior pituitary. Increased plasma osmolality and/or low blood volume triggers ADH release, which inserts aquaporin channels in the kidney collecting ducts to reabsorb water and produce darker, more concentrated urine.

When Sal goes to the bathroom, he notices that his urine is very dark. He knows this means he is dehydrated, so he makes sure to drink extra water. Which hormone is MOST responsible for causing Sal's urine to darken, warning him his homeostasis is off?

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