Question

Normal red
D100e cell
Sickle cell
Hemoglobin beta chain in sickle cell
GGA CTC CTC
GOA CẶC CTC
Normal celli
Sickle cell
What type of mutation error has occurred to cause the disorder shown? (1 point)
• insertion
• deletion
frameshift
C
substitution

Answer 1

Substitution — a single-base (point) missense mutation. In sickle cell the codon for glutamic acid is changed to one for valine (single nucleotide change), not an insertion/deletion or frameshift.