Question

Cystic fibrosis is an inherited disorder that is caused when three bases are accidentally removed from the CFTR gene. Which of the following is true about cystic fibrosis?(1 point)ResponsesCystic fibrosis is caused by a deletion mutation.Cystic fibrosis is caused by a deletion mutation.The affects of cystic fibrosis only impact women.The affects of cystic fibrosis only impact women.Cystic fibrosis is a silent disorder, it has no symptoms.Cystic fibrosis is a silent disorder, it has no symptoms.It is not known why cystic fibrosis happens in people

Answer 1

Cystic fibrosis is caused by a deletion mutation.

Specifically, the common ΔF508 CFTR mutation is the deletion of three nucleotides (an in‑frame deletion) removing a phenylalanine residue, which causes the CFTR protein to misfold; CF is an autosomal recessive disorder that affects both males and females and is not silent.