Question

A scientist wants to determine if two DNA samples came from the same person. Which combination of techniques would be most useful?
Responses

PCR followed by restriction enzyme analysis and gel electrophoresis
PCR followed by restriction enzyme analysis and gel electrophoresis

Only PCR amplification
Only PCR amplification

Only gel electrophoresis
Only gel electrophoresis

Only restriction enzyme analysis

Answer 1

PCR followed by restriction enzyme analysis and gel electrophoresis.

Reason: PCR amplifies informative DNA regions, restriction digestion reveals sequence-dependent fragment differences (RFLPs), and gel electrophoresis separates the fragments so you can compare band patterns between the two samples.