Question

Consider the three different types of stem cells. Each one's ability to differentiate into new cells is slightly different. One type can differentiate into any cell, while another can only become specific cells. Select the answer that places the three types in the correct order, from widest range of differentiation to least able to differentiate (specific).
• pluripotent, totipotent, multipotent
• totipotent, multipotent, pluripotent
• totipotent, pluripotent, multipotent
• pluripotent, multipotent, totipotent

Answer 1

Totipotent, pluripotent, multipotent

Totipotent cells can form all cell types including extraembryonic tissues (e.g., zygote), pluripotent cells can form almost any body cell but not extraembryonic tissues (e.g., embryonic stem cells), and multipotent cells are limited to a specific lineage (e.g., hematopoietic stem cells).