Hollinger was recently diagnosed with major depressive disorder. Which neurotransmitters are most likely in undersupply in Hollinger's brain?

Question

a
Oxytocin and gamma-aminobutyric acid (GABA)
b
Acetylcholine (ACh) and histamine
c
Dopamine and acetylcholine (Ach)
d
Serotonin and norepinephrine

Answer 1

In cases of major depressive disorder (MDD), the neurotransmitters most commonly associated with the condition and often thought to be in undersupply are serotonin and norepinephrine. Therefore, the correct answer is:

d. Serotonin and norepinephrine.