To solve the expression \( \frac{4}{6} - \frac{1}{6} \), you can simply subtract the fractions since they have the same denominator.
\[ \frac{4}{6} - \frac{1}{6} = \frac{4 - 1}{6} = \frac{3}{6} \]
Next, simplify \( \frac{3}{6} \):
\[ \frac{3}{6} = \frac{1}{2} \]
So, the final answer is:
\[ \frac{1}{2} \]