Which one of the following is true regarding Androgen-binding Protein?

It inhibits the release of FSH

It binds Testosterone to promote Spermatogenesis

It binds to Inhibin in a negative feedback loop of Spermatogenesis

It inhibits the release of GnRH

1 answer

The correct statement regarding Androgen-binding Protein (ABP) is:

It binds Testosterone to promote Spermatogenesis.

ABP is produced by Sertoli cells in the testes and is responsible for binding to testosterone and dihydrotestosterone, thus increasing the local concentration of these androgens in the seminiferous tubules, which is essential for promoting spermatogenesis.

The other statements listed are not true regarding ABP's function.