How does the combination of salt, soap, and alcohol work together to extract DNA?

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Salt warms DNA, soap makes it slippery, and alcohol shrinks it.
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Salt changes DNA color, soap mixes it, and alcohol heats it.
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Soap breaks membranes, and salt and alcohol help DNA clump together.
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Salt dissolves DNA, soap cleans it, and alcohol colors it.

1 answer

The correct explanation of how the combination of salt, soap, and alcohol works together to extract DNA is:

Soap breaks membranes, and salt and alcohol help DNA clump together.

Here's a brief overview of how they work together during DNA extraction:

  1. Soap (or detergent) breaks down cell membranes, which are made of lipids, allowing the cellular components (including DNA) to be released into the solution.

  2. Salt helps to stabilize the DNA and neutralize the negative charge on its phosphate backbone, which allows the DNA strands to come together and clump.

  3. Alcohol (often ethanol or isopropanol) is less polar than water, and when added, it causes the DNA to precipitate out of the solution, making it visible as a cloudy substance that can be spooled out.

This combination effectively isolates and allows for the extraction of DNA from cellular material.