Case summery

Bogalech tadesse is 18 yrs old girl comes to emergency OPD with muscle tremor , sweating and confusion.on inspection there was a flush of foul smelling chemical on her chin, neck and right hand and her dress was souked with foul smelling chemical, on palpation her abdomen was rigid.

Mini case
1. What will be your management option, if the client reaches to your health facility early?
2. What will be your management option if the client reaches to your facility lately?
3. What type of management should have to be prioritized after starting treatment, if her BP becomes 70/60 mmHg, urine output 0.3 ml/kg /hrs, pupil size no change, and sweating continuous.

1 answer

Based on the clinical presentation of Bogalech Tadesse, it is highly suggestive of exposure to a toxic substance, possibly a chemical agent. The symptoms of muscle tremor, sweating, confusion, and a foul-smelling chemical coating her body indicate potential toxicity, possibly related to pesticides, solvents, or other hazardous materials. The management will depend on the timing of her arrival at the health facility. Here’s an outline of the management approaches:

1. Management Options if the Client Reaches Early:

  • Immediate Decontamination:
    • Remove the patient’s clothing to prevent further absorption of the chemical.
    • Irrigate the skin with copious amounts of water and soap for at least 15-20 minutes (if safe for the chemical involved).
  • Airway Management:
    • Ensure patency of the airway and provide supplemental oxygen if needed.
  • Vital Signs Monitoring:
    • Monitor vital signs closely, especially heart rate, blood pressure, and respiration rate.
  • Symptomatic Treatment:
    • Administer fluids (e.g., IV normal saline) to maintain hydration.
    • If there are signs of cholinergic toxicity (e.g., excessive sweating, tremors), consider atropine as an antidote.
  • Supportive Care:
    • If confused, consider placing the patient in a safe environment or close monitoring.
  • Possible Specific Antidote Administration:
    • If specific to a known toxin (like organophosphate poisoning), administer appropriate antidotes.

2. Management Options if the Client Reaches Late:

  • Immediate Assessment:
    • Conduct a thorough assessment of vital signs, level of consciousness, and signs of organ dysfunction.
  • Airway Management:
    • Intubation may be necessary if there is significant respiratory distress or decreased consciousness.
  • Intravenous Fluids:
    • Start IV fluids to manage hypotension and possible renal impairment.
  • Antidote Administration:
    • If organophosphate poisoning is suspected and the patient presents late, administer atropine and pralidoxime (if indicated).
  • Laboratory Tests:
    • Conduct appropriate serum tests (e.g., toxicology screen, electrolytes, renal function tests) to assess organ function and toxicity levels.
  • Monitoring and Support:
    • Closely monitor for signs of complications such as seizures, respiratory depression, or cardiac issues.
  • Possibly Admission to an Intensive Care Unit:
    • If the patient has severe toxicity or organ compromise, transfer to an ICU for advanced monitoring and management.

3. Management Prioritization with Hypotension and Oliguria:

If Bogalech’s condition includes a blood pressure of 70/60 mmHg, urine output of 0.3 ml/kg/hr, unchanged pupil size, and continuous sweating:

  • Immediate Fluid Resuscitation:
    • Administer IV fluids rapidly (start with crystalloids like normal saline or lactated Ringer's solution) to stabilize blood pressure.
  • Vasopressor Support:
    • If hypotension persists despite adequate fluid resuscitation, initiate vasopressors (e.g., norepinephrine) to maintain adequate perfusion pressure.
  • Monitor Renal Function:
    • Assess urine output and consider nephrology consultation if oliguria persists.
  • Electrolyte Management:
    • Monitor and correct electrolyte imbalances as needed (especially potassium and acid-base status).
  • Continuous Monitoring:
    • Ongoing assessment of vital signs, mental status, and urine output will guide further management.

In all cases, the specific chemical exposure will significantly influence treatment protocols, so identifying the agent, if possible, remains critical for targeted management.