To change the equation
\[ -\frac{5}{4}x + \frac{5}{3}y = 8 \]
to standard form, which is typically represented as \(Ax + By = C\) where \(A\), \(B\), and \(C\) are integers, we should eliminate the fractions.
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The denominators in the equation are 4 and 3. To eliminate the fractions, we can find a common multiple of 4 and 3, which is 12.
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We can multiply the entire equation by 12 to eliminate the fractions:
\[ 12 \left(-\frac{5}{4}x\right) + 12 \left(\frac{5}{3}y\right) = 12 \cdot 8 \]
This results in:
\[ -15x + 20y = 96 \]
Now the equation is in standard form \(Ax + By = C\), where \(A = -15\), \(B = 20\), and \(C = 96\).
Among the options given, none of the direct multiplications by -4, -5, or 5 would yield the proper elimination of fractions. Therefore, the answer would be:
None of these steps can be taken.
However, multiplying by 12 would be the best choice to convert the equation directly to its standard form.