The ideas expressed in the excerpt most directly emerge from a larger debate over British Parliament’s decision to:
(Choice C) limit westward expansion beyond the Appalachian Mountains.
Colonel William Eyre’s statement reflects concerns about maintaining trade relations, preventing conflicts with Native Americans, and managing colonial expansion, all of which were connected to British policies aimed at controlling westward movement after the French and Indian War, particularly the Proclamation of 1763 which sought to limit colonial encroachment on Native lands.