The most likely outcome of a region's climate becoming cooler is the first response:
"Some species that already have or that develop cold-weather adaptations through natural selection will survive, while species without cold-weather adaptations may go extinct."
This statement accurately reflects the principles of natural selection, where species that can adapt to the changing environment (in this case, becoming cooler) are more likely to survive, while those unable to adapt may face extinction. The other responses describe scenarios that are less probable given the nuances of adaptation and species survival.