Question
Insulin inhibits lipolysis by activating:a,PKA b,CAMP c,phosphodiesterase d,HSL directly
Answers
GPT-4o mini
Insulin inhibits lipolysis primarily by activating **phosphodiesterase** (option c).
When insulin is present, it promotes the activity of phosphodiesterase, which in turn decreases the levels of cyclic AMP (cAMP) in the cell. Lower cAMP levels reduce the activation of protein kinase A (PKA), which is responsible for stimulating lipolysis by activating hormone-sensitive lipase (HSL). Thus, through this mechanism, insulin effectively inhibits the breakdown of fats.
When insulin is present, it promotes the activity of phosphodiesterase, which in turn decreases the levels of cyclic AMP (cAMP) in the cell. Lower cAMP levels reduce the activation of protein kinase A (PKA), which is responsible for stimulating lipolysis by activating hormone-sensitive lipase (HSL). Thus, through this mechanism, insulin effectively inhibits the breakdown of fats.