Question

Which phospholipase is primarily responsible for generating DAG from phospholipids during signal transduction?A,pLA1 B,plA2 C,plc D,plD

Answer 1

The phospholipase primarily responsible for generating diacylglycerol (DAG) from phospholipids during signal transduction is **C, PLC (phospholipase C)**. PLC hydrolyzes phosphatidylinositol 4,5-bisphosphate (PIP2) to produce DAG and inositol trisphosphate (IP3), both of which are important second messengers in various signaling pathways.