Question

Insulin inhibits lipolysis by activating

Answer 1

Insulin inhibits lipolysis primarily by activating **lipoprotein lipase (LPL)** and inhibiting hormone-sensitive lipase (HSL). When insulin is released, it acts on adipocytes (fat cells) to promote the storage of fat by facilitating the uptake of glucose and fatty acids and preventing the breakdown of triglycerides into free fatty acids and glycerol. This occurs through the activation of signaling pathways that increase LPL activity and decrease the activity of HSL, thus promoting lipid storage rather than mobilization.