For the first question regarding Chargaff's discovery, the correct choice that was NOT indicated is:
C When pairing nucleotides, you must pair purines with purines and pyrimidines with pyrimidines.
Chargaff's rules indicate that adenine pairs with thymine and guanine pairs with cytosine, which is consistent with purines (A and G) pairing with pyrimidines (T and C), rather than purines being paired with each other.
For the second question, the correct choice that must also be universal among all organisms is:
C The codons in all organisms' DNA code for the same amino acids.
This statement is true because the genetic code is universal for all living organisms, meaning that the same codon will code for the same amino acid across different species. Meanwhile, options A and B are not true, as organisms can have entirely different proteins and varying amounts of DNA. Option D also holds true only for specific cases rather than universally across all organisms.