Question
AATGTAAG
Part 3: Analyze the Mutation
7. Was the protein sequence affected?
☐ No (Silent) ☐ Yes (Harmful) ☐ Yes (Beneficial)
Part 3: Analyze the Mutation
7. Was the protein sequence affected?
☐ No (Silent) ☐ Yes (Harmful) ☐ Yes (Beneficial)
Answers
GPT-4o mini
To determine whether the protein sequence is affected by the mutation represented by the sequence "AATGTAAG," we first need to consider how this sequence corresponds to codons in mRNA and subsequently translates into an amino acid sequence.
1. **Transcription to mRNA**: The DNA sequence "AATGTAAG" can be converted to mRNA (considering the coding strand) by replacing T (thymine) with U (uracil):
- DNA: AAT GTT AAG
- mRNA: AAU GUU AAG
2. **Translation to Amino Acids**: Using the genetic code, we can translate the mRNA sequence into amino acids:
- AAU → Asparagine (N)
- GUU → Valine (V)
- AAG → Lysine (K)
So, the original protein sequence corresponding to "AATGTAAG" is N-V-K.
3. **Impact of Mutation**: To analyze the impact of the mutation, we need to compare the original sequence with the mutated sequence. If the modified sequence changes any of the amino acids translated from the mRNA codons, we need to determine if the changes are harmful, beneficial, or silent.
Without knowing the specific details of the point of mutation or the original sequence prior to the mutation, we cannot definitively say whether the protein sequence was affected. Thus, the answer will depend on that context.
If you provide the original sequence or more information about the mutation (e.g., what the original nucleotide(s) were or what they changed to), we can arrive at a conclusion about whether the protein is affected and the nature of that effect.
In the absence of that information, choose from:
☐ No (Silent) ☐ Yes (Harmful) ☐ Yes (Beneficial)
Please provide more context or the original sequence for a precise analysis!
1. **Transcription to mRNA**: The DNA sequence "AATGTAAG" can be converted to mRNA (considering the coding strand) by replacing T (thymine) with U (uracil):
- DNA: AAT GTT AAG
- mRNA: AAU GUU AAG
2. **Translation to Amino Acids**: Using the genetic code, we can translate the mRNA sequence into amino acids:
- AAU → Asparagine (N)
- GUU → Valine (V)
- AAG → Lysine (K)
So, the original protein sequence corresponding to "AATGTAAG" is N-V-K.
3. **Impact of Mutation**: To analyze the impact of the mutation, we need to compare the original sequence with the mutated sequence. If the modified sequence changes any of the amino acids translated from the mRNA codons, we need to determine if the changes are harmful, beneficial, or silent.
Without knowing the specific details of the point of mutation or the original sequence prior to the mutation, we cannot definitively say whether the protein sequence was affected. Thus, the answer will depend on that context.
If you provide the original sequence or more information about the mutation (e.g., what the original nucleotide(s) were or what they changed to), we can arrive at a conclusion about whether the protein is affected and the nature of that effect.
In the absence of that information, choose from:
☐ No (Silent) ☐ Yes (Harmful) ☐ Yes (Beneficial)
Please provide more context or the original sequence for a precise analysis!