In two-point perspective, you generally depict objects using two vanishing points on the horizon line. To draw a city block in two-point perspective, you would typically show two streets that converge towards two separate vanishing points on the horizon.
Therefore, the best response for how to draw a city block in two-point perspective would be: "show two streets that intersect and vanish at different points on the horizon." This correctly represents the key characteristics of two-point perspective.