To calculate \( \frac{4}{9} \times -3 \), you can multiply the fraction by the whole number:
\[ \frac{4}{9} \times -3 = \frac{4 \times -3}{9} = \frac{-12}{9} \]
Next, simplify the fraction \( \frac{-12}{9} \):
\[ \frac{-12}{9} = \frac{-4}{3} \]
Thus, \( \frac{4}{9} \times -3 = -\frac{4}{3} \).