3TC is an antiretroviral treatment used to prevent HIV infection from becoming AIDS. After treatment with 3TC, the HIV population in a patient consists entirely of 3TC-resident virus particles. What bets explains this phenomenon?

A. HIV can change its surface proteins through mutations and resist vaccines
B. The patient became re-infected with 3TC-resistant viruses after the initial exposure
C. The drug caused RNA changes to occur, creating a resistance to the once applicable drug
D. A few drug-resistant viruses were present at the start of the treatment and selective pressures increased their frequency
I think itโ€™s A

1 answer

D

Explanation:

3TC is an antiretroviral treatment used to prevent HIV infection from becoming AIDS. After treatment with 3TC, the HIV population in a patient consists entirely of 3TC-resistant virus particles. What best explain this phenomenon?