The correct response to how the concept of Manifest Destiny influenced Isaac Stevens in his dealings with Native American tribes is:
Stevens justified removing the Native Americans' claim on the land because he believed the U.S. should expand throughout North America.
Stevens, as a proponent of Manifest Destiny, believed in the inevitable expansion of the United States across the continent. This belief often led to the justification of actions taken against Native American tribes, as he and others viewed the acquisition of land for American settlers as a paramount objective, often at the expense of existing tribal claims.