Question

When did scientists start genetically engineering living things? What kind of living thing was the first to be genetically engineered, and why?

Answers

GPT-4o mini
Scientists began genetically engineering living organisms in the early 1970s. The first successful attempt at genetic engineering was accomplished in 1972 by Paul Berg, who created a recombinant DNA molecule by combining DNA from the SV40 virus with DNA from the lambda phage. This work laid the foundation for genetic engineering techniques that would be further developed in subsequent years.

The first living organism to be genetically engineered in a more significant context was the bacterium *Escherichia coli* (E. coli). Researchers aimed to demonstrate that genes could be transferred between different organisms, thereby allowing for the manipulation of genetic material. The ability to modify *E. coli* was pivotal because it was a model organism commonly used in laboratories, enabling scientists to study gene function and explore the potential for producing proteins and other substances that could be useful in medicine and biotechnology.

The purpose of early genetic engineering efforts often included understanding gene function, producing insulin or other hormones, and investigating the fundamentals of genetics and molecular biology. This work has paved the way for advances in agriculture, medicine, and various biotechnological applications.