Question

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is the failure of sister chromatids to separate normally, resulting in a cell with the incorrect number of chromosomes.

Answer 1

The phenomenon you are describing is called **nondisjunction**. Nondisjunction occurs during cell division—specifically during meiosis or mitosis—when sister chromatids fail to separate properly. This results in daughter cells that have an abnormal number of chromosomes, either having an extra chromosome (trisomy) or missing one (monosomy). Nondisjunction can lead to various genetic disorders, such as Down syndrome, which is caused by an extra copy of chromosome 21.