The best response to the question is: The positive effects outweigh the negative effects in certain environments.
This option suggests that in specific environments, the advantages provided by an enlarged right ventricle (such as increased oxygen intake) can be significant enough to offset the negative consequences (like the risk of pulmonary hypertension), leading to a net positive effect on survival and reproduction within those contexts. Natural selection can thus favor traits that may have both positive and negative consequences depending on environmental conditions.