The correct response is:
Scientists observe the frequency of the different forms of the gene and how it changes in response to the environment.
This option demonstrates natural selection because it highlights how variations in the gene may confer advantages or disadvantages based on environmental factors. In Darwin's finches, changes in beak size and shape in response to available food sources are a classic example of natural selection, where the frequency of certain gene variations (like those affecting traits) changes over time due to environmental pressures.