To solve the expression \( \frac{41}{4} - \frac{22}{4} \), you can subtract the numerators since the denominators are the same.
\[ \frac{41 - 22}{4} = \frac{19}{4} \]
Now, let's check the responses provided:
- \( \frac{3}{4} \)
- \( \frac{5}{4} \)
- \( \frac{7}{4} \)
- \( \frac{13}{4} \)
- \( \frac{21}{4} \)
The correct answer \( \frac{19}{4} \) does not appear in the list. Therefore, none of the given options apply based on the calculation \( \frac{41}{4} - \frac{22}{4} = \frac{19}{4} \).