Betel nut ranks as the fourth most widely used psychoactive substance in the world, following caffeine, alcohol, and nicotine.
More than 600 million individuals, primarily in South Asia and Oceania, chew betel nut, which plays a significant role in their cultural and social identities.
Archaeological evidence indicates that its use dates back around 8,000 years in Thailand.
In addition to being valued as "green gold" by grassroots communities, betel nut is also seen as a peace symbol, traditionally involved in peace ceremonies, bride price negotiations, and rituals to dispel evil spirits.
The oral microbiota is a crucial factor in human health.
In Papua New Guinea, the practice of chewing betel nut has been ongoing for at least 3,000 years and has notably increased in the past century.
Numerous studies around the globe have consistently linked betel nut chewing to periodontal diseases.
There are taxonomic variations associated with betel nut consumption.
The practice of chewing betel nut significantly disrupts the oral microbiome of individuals in Papua New Guinea.
The challenge of managing the population's betel nut chewing habits, combined with the rising rates of oral diseases, raises concerns that need to be addressed. Our study aims to advocate for restrictions on its use and promote education and awareness programs regarding the risks associated with betel nut consumption.