Question

Original DNA: AAT TTA ACG TAG CTA TGA

(same as last question, copy paste) original mRNA:

(same as last question, copy paste) original Amino Acid sequence (use three letter abbreviation):

Mutation #5 DNA: AAT TTA AGT AGC TAT GA

Mutation #5 mRNA:

Mutation #5 Amino Acids:

Mutation #5 Type:

Answer 1

To analyze the original DNA and the mutated DNA sequence, we start with the original sequence provided:

**Original DNA:**
AAT TTA ACG TAG CTA TGA

### Step 1: Transcription to mRNA
Let's convert the original DNA into mRNA by replacing thymine (T) with uracil (U):

**Original mRNA:**
UUA AAU UGC AUC GAU ACU

### Step 2: Translation to Amino Acids
Now, we translate the mRNA into an amino acid sequence using the genetic code.

**Codons:**
- UUA -> Leu (Leucine)
- AAU -> Asn (Asparagine)
- UGC -> Cys (Cysteine)
- AUC -> Ile (Isoleucine)
- GAU -> Asp (Aspartic acid)
- ACU -> Thr (Threonine)

**Original Amino Acid Sequence (3-letter abbreviation):**
Leu - Asn - Cys - Ile - Asp - Thr

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Now, let's analyze `Mutation #5`.

**Mutation #5 DNA:**
AAT TTA AGT AGC TAT GA

### Step 3: Transcription of Mutated DNA to mRNA
We convert the mutated DNA into mRNA:

**Mutation #5 mRNA:**
UUA AAU UCA UCG AUA CU

### Step 4: Translation to Amino Acids
Next, we will translate the mutated mRNA into the corresponding amino acids.

**Codons:**
- UUA -> Leu (Leucine)
- AAU -> Asn (Asparagine)
- UCA -> Ser (Serine)
- UCG -> Ser (Serine)
- AUA -> Ile (Isoleucine)
- CU -> (Incomplete codon, we'll ignore as it doesn't contribute to a full amino acid)

**Mutation #5 Amino Acids (3-letter abbreviation):**
Leu - Asn - Ser - Ser - Ile

### Step 5: Type of Mutation
To determine the type of mutation, we note that the original sequence had "ACG" (coding for Cys) replaced with "AGT" (coding for Ser), which indicates a point mutation. This specific change led to a change in the amino acid produced (from Cys to Ser), which classifies this as a missense mutation.

**Mutation #5 Type:**
Missense mutation

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# Summary:
- **Mutation #5 mRNA:** UUA AAU UCA UCG AUA CU
- **Mutation #5 Amino Acids:** Leu - Asn - Ser - Ser - Ile
- **Mutation #5 Type:** Missense mutation