To find out how many more bagels Sherri needs to sell in order to make a profit, we first subtract the number of bagels she has already sold (75) from the target number of bagels she needs to sell (450):
450 - 75 = 375
This means that she needs to sell at least 375 more bagels. Therefore, we can write the inequality as:
b ≥ 375
So the correct response is:
b ≥ 375