The correct choice is:
The sequence of amino acids determines the shape of the enzyme, which determines the molecules that the enzyme can bind.
This statement reflects the relationship between the amino acid sequence (primary structure), the folding of the protein (secondary and tertiary structures), and the specific shape of the enzyme that allows it to interact with and bind to its target molecules (substrates) effectively. Each enzyme has a specific active site formed by its unique sequence of amino acids, which is complementary to the shape of the target molecule, facilitating the enzyme's function.