Native Americans had a variety of reactions to the Corps of Discovery, depending on their specific circumstances, cultural backgrounds, and the nature of their interactions. However, the most representative reaction is best summarized as follows: They gave food, supplies, and shelter to the Corps.
Many tribes were generally welcoming and provided assistance to Lewis and Clark during their journey, seeing them as potential allies or trading partners. There were instances of hostility and misunderstandings, but many Native American groups recognized the opportunity for trade and cooperation.