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Create Punnett Squares and Pedigree

Generation 1: Alice and Bob Washington are both carriers of a recessive genetic mutation.
They do not show the mutation but have the genotype "Rr".
Generation 2: Alice and Bob have three children: Grace, Henry, and Emma.
• Grace: Rr (Carrier, but does not show the mutation)
• Henry: RR (Neither carrier nor affected)
• Emma: rr (Shows the genetic mutation)
Generation 3: Emma marries Michael, who is not a carrier (RR). They have four children:
Jack, Lily, Noah, and Ava.
• Jack: Rr (Carrier, but does not show the mutation)
• Lily: Rr (Carrier, but does not show the mutation)
• Noah: Rr (Carrier, but does not show the mutation)
• Ava: Rr (Carrier, but does not show the mutation)
Generation 4: Jack marries Emily, who is also a carrier (Rr). They have three children:
Oliver, Sophia, and Mia.
• Oliver: RR (Neither carrier nor affected)
• Sophia: Rr (Carrier, but does not show the mutation)
• Mia: rr (Shows the genetic mutation)
Generation 5: Sophia marries Ethan, who is not a carrier (RR). They have two children:
Jacob and Isabella.
• Jacob: RR (Neither carrier nor affected)
• Isabella: Rr (Carrier, but does not show the mutation)
Generation 6: Isabella marries James, who is a carrier (Rr). They have three children:
Lucas, Charlotte, and Benjamin.
• Lucas: RR (Neither carrier nor affected)
• Charlotte: Rr (Carrier, but does not show the mutation)
• Benjamin: rr (Shows the genetic mutation)
Generation 7: Charlotte marries Daniel, who is not a carrier (RR). They have two children:
Amelia and William.
• Amelia: RR (Neither carrier nor affected)
• William: Rr (Carrier, but does not show the mutation)

1 answer

To visualize the genetic inheritance through the generations you described, we will create a Punnett square for each generation where applicable, along with a pedigree chart to outline the family relationships and the health statuses of the individuals.

Generation 1: Alice (Rr) and Bob (Rr)

Punnett Square:

| | R | r | |----|----|----| | R | RR | Rr | | r | Rr | rr |

Offspring Genotypes:

  • 25% RR (Neither carrier nor affected) - not applicable in Generation 2
  • 50% Rr (Carriers, do not show mutation)
  • 25% rr (Shows the genetic mutation)

Generation 2: Alice and Bob's Children

  • Grace: Rr (carrier)
  • Henry: RR (not affected)
  • Emma: rr (shows mutation)

Pedigree Chart for Generations 1 and 2:

     Alice (Rr) ------ Bob (Rr)
          |                 |
     -------------------------
    |                 |                     |
 Grace (Rr)     Henry (RR)       Emma (rr)

Generation 3: Emma (rr) and Michael (RR)

Punnett Square:

| | R | R | |----|----|----| | r | Rr | Rr | | r | Rr | Rr |

Offspring Genotypes:

  • 100% Rr (Carriers, do not show mutation)

Children:

  • Jack: Rr
  • Lily: Rr
  • Noah: Rr
  • Ava: Rr

Pedigree Chart for Generation 3:

        Emma (rr) ------ Michael (RR)
          |                                |
    ---------------------------------------
    |           |            |            |
  Jack (Rr)  Lily (Rr)  Noah (Rr)   Ava (Rr)

Generation 4: Jack (Rr) and Emily (Rr)

Punnett Square:

| | R | r | |----|----|----| | R | RR | Rr | | r | Rr | rr |

Offspring Genotypes:

  • 25% RR (not affected)
  • 50% Rr (carriers)
  • 25% rr (shows mutation)

Children:

  • Oliver: RR
  • Sophia: Rr
  • Mia: rr

Pedigree Chart for Generation 4:

         Jack (Rr) ------ Emily (Rr)
                |                   |
         ---------------------------
         |            |            |
      Oliver (RR)  Sophia (Rr)  Mia (rr)

Generation 5: Sophia (Rr) and Ethan (RR)

Punnett Square:

| | R | R | |----|----|----| | R | RR | RR | | r | Rr | Rr |

Offspring Genotypes:

  • 50% RR (not affected)
  • 50% Rr (carriers)

Children:

  • Jacob: RR
  • Isabella: Rr

Pedigree Chart for Generation 5:

       Sophia (Rr) ------ Ethan (RR)
                |                   |
         -----------------------
         |                    |
      Jacob (RR)        Isabella (Rr)

Generation 6: Isabella (Rr) and James (Rr)

Punnett Square:

| | R | r | |----|----|----| | R | RR | Rr | | r | Rr | rr |

Offspring Genotypes:

  • 25% RR (not affected)
  • 50% Rr (carriers)
  • 25% rr (shows mutation)

Children:

  • Lucas: RR
  • Charlotte: Rr
  • Benjamin: rr

Pedigree Chart for Generation 6:

          Isabella (Rr) ------ James (Rr)
                     |                      |
              -------------------
              |            |            |
          Lucas (RR)  Charlotte (Rr)  Benjamin (rr)

Generation 7: Charlotte (Rr) and Daniel (RR)

Punnett Square:

| | R | R | |----|----|----| | R | RR | RR | | r | Rr | Rr |

Offspring Genotypes:

  • 50% RR (not affected)
  • 50% Rr (carriers)

Children:

  • Amelia: RR
  • William: Rr

Pedigree Chart for Generation 7:

        Charlotte (Rr) ------ Daniel (RR)
                   |                      |
                ---------------
                |             |
          Amelia (RR)    William (Rr)

Comprehensive Pedigree Chart:

This overarching chart would connect all generations visually:

                        Alice (Rr) ------ Bob (Rr)
                        |                                 |
             ---------------------------      
             |                  |                |
         Grace (Rr)     Henry (RR)      Emma (rr)
                                             |
                                     Michael (RR)
                                             |
                      ------------------------------------
                      |                 |               |               |   
                 Jack (Rr)      Lily (Rr)      Noah (Rr)    Ava (Rr)
                      |
                Emily (Rr)
                      |
         -----------------------------------
         |               |               |
     Oliver (RR)   Sophia (Rr)    Mia (rr)
                           |
                     Ethan (RR)
                           |
             ------------------------
             |                    |
        Jacob (RR)        Isabella (Rr)
                                 |
                           James (Rr)
                                 |
                  ---------------------------------
                  |                |               |
            Lucas (RR)   Charlotte (Rr)   Benjamin (rr)
                                |
                          Daniel (RR)
                                |
                     -----------------
                     |               |
              Amelia (RR)    William (Rr)

This pedigree chart and the associated Punnett squares clearly show the inheritance of the genetic mutation through the generations.

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