The statement that is true regarding the genetic material of prokaryotes and eukaryotes is:
Eukaryotes have their DNA stored in a membrane-bound nucleus, while prokaryotes have their DNA in a region called the nucleoid.
In prokaryotes (like bacteria), the DNA is typically circular and located in a region called the nucleoid, which is not membrane-bound. In contrast, eukaryotes (like plants and animals) have linear DNA that is organized and stored within a membrane-bound nucleus.