The significant aspect of the transfer of power after the election of 1800 is:
It was peaceful despite the major differences between the two parties.
This election marked a pivotal moment in U.S. history, as it was the first time that power was transferred from one political party to another (from the Federalists to the Democratic-Republicans) without violence. Thomas Jefferson's election represented a shift in political power and served as a testament to the durability of the American political system.