Question
Hemophilia is a bleeding disorder that primarily affects males. Which of the following statements best explains why females are less likely to express the trait
The British Hemophilia Line
Queen
T Victoria Wing Edward V
Albert of Se-Churg-Gotse
Alfred Helene Louis
Hemy of Grand
Leopold
Item 12
Item 13
Item 14
(1 point)
When paired with a normal X, the affected x allele is masked (Xx), suppressing the trait. Since females have only X alleles, the probability increases.
Females have an XY chromosome pair, so the trait is frequently expressed
Males without an affected x allele always express the trait (XY)
When paired with a normal X, the affected x allele is masked (Xx), suppressing the trait. Since females have only X alleles, the probability decreases.
The British Hemophilia Line
Queen
T Victoria Wing Edward V
Albert of Se-Churg-Gotse
Alfred Helene Louis
Hemy of Grand
Leopold
Item 12
Item 13
Item 14
(1 point)
When paired with a normal X, the affected x allele is masked (Xx), suppressing the trait. Since females have only X alleles, the probability increases.
Females have an XY chromosome pair, so the trait is frequently expressed
Males without an affected x allele always express the trait (XY)
When paired with a normal X, the affected x allele is masked (Xx), suppressing the trait. Since females have only X alleles, the probability decreases.
Answers
GPT-4o mini
The best explanation for why females are less likely to express hemophilia, which is an X-linked recessive disorder, is:
**When paired with a normal X, the affected X allele is masked (Xx), suppressing the trait. Since females have two X chromosomes, they have a higher probability of carrying one normal X allele that can mask the affected allele.**
This means that while females can be carriers of the hemophilia trait (having one affected X chromosome and one normal X chromosome), they are less likely to express the disorder compared to males, who have only one X chromosome and will express the trait if their sole X chromosome carries the hemophilia allele.
**When paired with a normal X, the affected X allele is masked (Xx), suppressing the trait. Since females have two X chromosomes, they have a higher probability of carrying one normal X allele that can mask the affected allele.**
This means that while females can be carriers of the hemophilia trait (having one affected X chromosome and one normal X chromosome), they are less likely to express the disorder compared to males, who have only one X chromosome and will express the trait if their sole X chromosome carries the hemophilia allele.