The most accurate response is: Some humans are exposed to higher levels of ultraviolet radiation.
The ozone layer protects the Earth from harmful ultraviolet (UV) radiation from the sun. A "hole" in the ozone layer results in a decrease in this protection, leading to increased levels of UV radiation reaching the Earth's surface. Higher levels of UV radiation can lead to various health issues for humans, including an increased risk of skin cancer, cataracts, and other eye damage, as well as negative effects on the immune system.