Question

Following the first pregnancy with an Rh+ fetus, the immune system of an an Rh– woman produces anti-D antibodies. During her next pregnancy the baby is at risk of developing Hemolytic Disease of the Newborn (HDN), but only if which of the following is true?

Multiple choice question.

The baby's blood is Rh-.


The father's blood is Rh-.


The baby's blood is Rh+.


The mother's blood type has changed to Rh+.

Answers

GPT-4o mini
The correct answer is:

**The baby's blood is Rh+.**

In this scenario, an Rh– woman produces anti-D antibodies during her first pregnancy if her fetus is Rh+. In subsequent pregnancies, if her next baby is also Rh+, the anti-D antibodies can cross the placenta and attack the Rh+ red blood cells of the fetus, leading to Hemolytic Disease of the Newborn (HDN). If the next baby is Rh–, there is no risk of HDN, as the mother's antibodies would not attack the baby's red blood cells.

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